Pharmaceuticals
GSK and Ionis announce historic functional cure rates for chronic hepatitis B in Phase III trials with bepirovirsen, potentially transforming treatment for 250 million patients worldwide.
New ASCO data from Alpha Tau Medical (NASDAQ: DRTS) shows immune markers remain stable after treatment, a finding that could open the door to combination therapies in one of oncology's deadliest cancers. Pancreatic cancer is the third leading cause of cancer death in the United States. It kills
In May 2024, AstraZeneca completed a $1.05 billion acquisition of Amolyt Pharma, securing eneboparatide – a daily injectable therapy for hypoparathyroidism that had demonstrated promising Phase 2 data but had not yet completed Phase 3. The deal reflected big pharma's conviction that hormone replacement for hypoparathyroidism represents a
Biotechnology
MediWound has a product already on the market, no long-term debt, substantial non-dilutive government funding, and a Phase III asset going after a market dominated by a single 60-year-old drug Chronic wounds are not something most investors think about. But they should. More than 10 million Medicare beneficiaries in the
Biotechnology
Fractyl Health outlines ambitious 2026 roadmap positioning its Revita system as the first FDA-approved solution for maintaining weight loss after GLP-1 discontinuation, with pivotal clinical data expected this month.
GLP-1 drugs have reshaped the treatment of obesity and diabetes, and innovation in the category is accelerating. The FDA approval of an oral version of Wegovy for chronic weight management marked a major milestone, expanding access to GLP-1 therapy and offering a new option for patients reluctant to use injections.
Biotechnology
Ascletis Pharma announced FDA IND clearance for ASC30, an oral small molecule GLP-1 receptor agonist for diabetes treatment, marking a significant milestone in the competitive GLP-1 market with a differentiated approach to injectable peptide therapies.
Pharmaceuticals
January 4, 2026, marks a watershed moment in the global GLP-1 market as Canada becomes the first country where Novo Nordisk's blockbuster diabetes and weight-loss drug Ozempic loses patent protection. Leading the charge into this newly opened market is Toronto-based Vimy Pharma, a startup founded by former Novo
Biotechnology
Insilico Medicine announces an $888 million multi-year collaboration with Servier, representing one of the largest AI-driven drug discovery deals to date and validating the commercial viability of AI in pharmaceutical research.
Pharmaceuticals
Axsome Therapeutics announces FDA Priority Review for AXS-05 in treating Alzheimer's disease agitation, with a PDUFA target action date of April 30, 2026, offering hope for millions affected by this challenging behavioral symptom.
Pharmaceuticals
Johnson & Johnson's termination of its Phase 2b study for JNJ-95475939 serves as a stark reminder that even the world's largest healthcare companies face brutal realities in drug development, despite investing $1.25 billion in the acquisition just 18 months earlier.
Biotechnology
Denali Therapeutics' tividenofusp alfa achieves historic NEJM publication as the first brain-penetrant enzyme replacement therapy for Hunter syndrome, with FDA decision expected by April 5, 2026.